Mini-Review Leucine-Rich Repeat Proteins of Synapses

نویسندگان

  • Jaewon Ko
  • Eunjoon Kim
چکیده

Leucine-rich repeats (LRRs) are 20–29-aa motifs that mediate protein–protein interactions and are present in a variety of membrane and cytoplasmic proteins. Many LRR proteins with neuronal functions have been reported. Here, we summarize an emerging group of synaptic LRR proteins, which includes densin-180, Erbin, NGL, SALM, and LGI1. These proteins have been implicated in the formation, differentiation, maintenance, and plasticity of neuronal synapses. VC 2007 Wiley-Liss, Inc.

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تاریخ انتشار 2007